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System Biology BLASTn Protein Network Cellular Signaling Genetics

1. Perform a BLASTn search with the following sequence but only use 30 of the 50 bases. What was your best match? 5' ATGCT CTGGC CACGG CACTT GCGGA TCCCA TGATC TGTGC ACCTG CGATA 3' 3' TACGA CACCG GTGCC GTGAA CGCCT AGGGT ACTAG ACACG TGGAC GCTAT 5' Look to the right at the "E value" and record this number. Comment on the signif

Gene Expression Systems are figured.

Let's assume that I fould a valuable gene fragment (ex. DNA sequence homology with one of the human myosin II genes) 1. Before I proceed for therapeutic development, How would I know if this gene is actually expressed in humans? What method? 2. Now let's assume it is expressed in human. I wish to express the cDNA corre

It's regarding genotypes and linkages.

A hairy-winged (h) Drosophila female is mated with a yellow-bodied (y), white-eyed (w) male. The F1 are all normal. The F1 progeny are then crossed and the F2 that emerge are Females: Wild-type 757 Hairy 243 Males: Wild-type 390 Hairy 130 Yellow 4 White

Mutation and the experimental evolution of fitness

In a lab experiment we examined the evolutionary effects effects of genetic stress: a harmful recessive mutation (nub E and nub X)that was experimentally introduced into a population of flies hundreds of years ago. The goals were to assess the impact of nub on juvenile fitness, the impact of nub on adult fitness and to assess

Biology Questions

It is a good idea to check the assertion that 1.27 X 10 to the 30th power double-stranded DNA molecules of 100 base pairs each would weigh almost 140,000 tons. Hint: Start by using Avogadro's number (listed below) to determine how many moles of DNA are represented by this large number of base pairs. Assume an average mass of

Methods of forensic DNA profile analysis

More methods of VNTR analysis 1. Which of the following is NOT a part of the methods used in single locus probe analysis of VNTR regions of human DNA? Please explain the right answer. A. DNA extraction B. Restriction endonuclease digestion of DNA C. Gel electrophoresis D. Autoradiography E. Recombinant DNA

Forensic DNA Profile Analysis and VNTR alleles

The analysis of VNTR alleles in forensic DNA profile analysis is based on what common method of molecular biology? A. Cloning B. ELISA C. Immunoblotting D. PCR reactions E. Southern hybridization Provide the correct answer and a brief explanation of why the correct answer is correct. Thank you!

Forensic DNA Fingerprinting and the Variations of VNTR

2. The VNTR alleles analyzed in forensic DNA fingerprinting experiments are highly variable from individual to individual. How do the many VNTR alleles at a single locus differ from each other? A. the number of internal restriction endonuclease cleavage sites for the enzyme HaeIII B. the number of protein coding gene

Biology Problem

A genetic locus that is analyzed in many forensic and paternity testing laboratories is the human leukocyte antigen locus known as HLA-DQ alpha. There are four major alleles at this locus known as 1, 2, 3, and 4. How many different genotypes are possible for these four alleles? A. 8 B. 10 C. 12 D. 16 E. 24 Than

Human Genetics Quiz

Exams are approaching quickly and for review, can you please provide the correct answers for the following multiple-choice quiz on human genetics, along with an explanation of the correct answer. Thank you! BIOLOGY QUIZ: MULTIPLE CHOICE QUESTIONS ON HUMAN GENETICS 1. Red-green color blindness is X-linked in humans. If a

Genotype Biology Question

Irene's daughter is type A and her grandson's is type B+. She does not know the type of either father. She wants to know the possible blood types of the fathers in order for her grandson to be a B+? (a) B or O (b) A, B, AB or O (c) AB or B (d) A or B (e) A, B, or AB

Biology question about blood type

1. A mother wants to know the blood type of her son's father. What blood type would the father be if her son and herself are both type A+. Also, her (the mother's) brother is type 0 and her mom is A+. What blood type can the father be? The father could be: (a) A. A, AB, B, or O (b) Either A or B (c) Either A or O

Biology Question

If the mother of a child is blood type O+ and the child is A-, what blood type would the father be? Does the Rh factor of the child being - (negative) mean that one of the parents has to be negative? Both the parents are Rh - all of the siblings are Rh-as well. Could two Rh- parents give birth to a Rh+ child? and visa versa?

Biology Question

A man has type B blood and a woman has type AB blood. Can they produce a child with type O blood?" Is a type O possible in this situation? A. Possible B. Not possible

Molecular Genetics of Prokaryotes.

1. Which of the following is not part of the lac operon of E. coli? A. genes for inducible enzymes of lactose metabolism B. genes for the repressor, a regulatory protein C. gene for RNA polymerase D. a promoter, the RNA polymerase binding site E. the operator, the repressor binding site 2. (The role of the inducer of t

Produces a pedigree

How can i produce a peddigree that has 3 generations and a trait for Handedness what is the predicton of mode of inheritance?

Conjugational cross/gene order

Analyze the data in the Table and determine the relative order of the four lac alleles with respect to the flanking pro and ade loci.

Inefficient missense mutation suppressors

Hi. Can someone please explain the following answer to me: Q: Do you think that the mutated anticodon ACU (which inserts serine) can suppress a particular missense mutation? A: Yes, the mutated anticodon should insert serine at Trp codons. Thus, some missense mutants that have a Trp replacement in the defective protein mig

Test crosses are examined.

I have a phenotypically purple flowered pea plant with the flowers located along the stem. How do I determine the genotypes and do test crosses on the homozygous and heterozygous genotype and determine the genotype and phenotype ratios of each cross? The process is explained.

Guide for Population-Genetics Problems using the Hardy-Weinberg Equilibrium.

In a particular flower, a single pair of alleles determines the petal color (C). Red flowers have the genotype CR/CR (homozygous for CR), white flowers have the genotype Cr/Cr (homozygous for Cr) and pink flowers have the genotype CR/Cr (they are heterozygous). In a given population, 49 flowers had red petals, 42 had pink pe

Lethal genes in rabbit - pelger anomaly

Pelger anomaly in rabbits involves white blood cell nuclear segmentation. Rabbits homozygous [PP] to this condition are usually still born or die just after birth due to gross illformed skeletal structure. Pelgers are heterozygous [Pp] and normal rabbits are homozygous [pp]. What is the adult F2 phenotypic ratio in all pelger ma

Penetrance in abnormality of eye in flies

A series of crosses in a controlled environment in which all progeny were known to carry a dominant autosomal gene A that causes eye abnormality produced 600 normal flies and 1400 abnormal flies. What is the penetrance of this gene A in this particular experiment?

Blood transfusion is assessed.

A normal person receives blood transfusion from an individual having sickle cell trait. Will this transfusion affect the recipient? Why / why not? Ideas are justified.

Genotypic and phenotypic ratios in hair texture in dogs.

Wire hair in dogs is dominant over its recessive allele for smooth hair. A cross between heterozygous wire haired individuals produces F1 which are then test crossed. Determine from the expected progeny their phenotypic and genotypic ratios.

Lethality in Mexican hairless breed of dogs

Hairless condition in Mexican hairless breed of dogs is heterozygous [Hh] against the normal homozygous recessive [hh]. Puppies homozygous for H allele are born dead due to abnormalities in mouth and absence of external ears. If the average litter size at weaning is 6 in matings between hairless dogs, what is the expected number

Genetics Exercises: 5 Exercises on Crossings- Autosomal and Sex Linked genes

Complete the gene exercise. Refer to attachment. Exercise I We are going to begin by looking at some basic mating patterns, using a couple of eye color mutations in fruit flies. The normal fruit fly has brick red eyes. This is called the "wild type," because the vast majority of wild fruit flies have this co

Helping dyslexic students in and out of the classroom.

What if I have a student that is dyslexic...what are some things that I can do in the classroom, as a teacher to make things easier? Also, what are some tips that I can give the parents and what are some techniques that the school counselor can use when counseling the student?