Explore BrainMass

Construction of genetic map on the basis of transfer of gene

Four Hfr stains of E. coli are known to transfer their genetic material during conjugation in different sequences. Given the time of entry of the markers into the F- recipient:
A. Construct a genetic map that includes all of these markers. (12 points)
B. Label the time distance between adjacent gene pairs. (11 points)
C. Indicate the points at which the F factor is located for each of the strains. (4 points)

Hfr Strain 1 Markers arg thy met thr - -
Times in min 15 21 32 48 - -
Hfr Strain 2 Markers mal met thi thr try -
Times in min: 10 17 22 33 57 -
Hfr Strain 3 Markers phe his bio azi thr thi
Times in min 6 11 33 48 49 60
Hfr Strain 4 Markers his phe arg mal - -
Times in min 18 23 35 45 - -

© BrainMass Inc. brainmass.com July 15, 2018, 3:51 pm ad1c9bdddf

Solution Preview

A. Here is the genetic map including all the markers (drawn on the basis of distance between the entry of markers into the F- recipient).
(fig 1 in attachment)

Here is the distribution of markers on the chromosome along with the time difference (in minutes) between different markers. (fig 2 in attachment)

B. The ...