This solution details the types of infections that are common in three types of inherited immunodeficienies: complement C8 deficiency; X-linked agammaglobulinaemia (Bruton's disease); and selective IgA deficiency. It explains the underlying basis of why these patients are susceptible to these particular infections.
For each of the following conditions: 1) complement C8 deficiency: a defect that results in the functional absence of the eighth complement cascade. C8 is involved in the complement lytic pathway. 2) X- linked agammaglobulinaemia (Bruton's disease) :This affects an enzyme that is required for B cell development so pre B cell