Share
Explore BrainMass

Genetics

Pedigree Inheritance Pattern

Four patterns of inheritance and four pedigrees are shown below. Assume that individuals marrying into the family are homozygous for the wild-type allele. Match each of the inheritance patterns with a pedigree. (a) Autosomal recessive _________ (b) Y-linked trait _________ (c) X-linked recessive _________ (d) Autosomal domi

Pedigree Inheritance Pattern of Huntington's Disease

Please see attachment for pedigree inheritance pattern of Huntington's disease. Huntington's disease is a late-onset disease caused by a single, dominant mutation. The following pedigree is for a family with a history of Huntington disease. Those individuals who are already suffering from the disease are shaded black. However

biosynthetic pathway

The production of the purple pigment anthocyanin in flowers is accomplished via a biosynthetic pathway. A biosynthetic pathway consists of a series of enzymatic reactions resulting in the creation of a final end product via several intermediate metabolites. An example of a biosynthetic pathway is shown below: S

Alleles in beetles

See attached for the picture the questions are referencing. ln the beetles described in the animation, there were two alleles for color, brown and green. Suppose that you discover a very small population of these beetles, consisting of the individuals shown below. How can you calculate the frequency of each allele in ihis

Gene Therapy

I need help answering the following questions: 1. Description of gene therapy and how it works. 2. What are the principles that underlie gene therapy? Please provide academic references to support your response. Thanks

Calculate the fraction of the volume of E.coli is DNA

A cell of E. coli contains about 10-14 g if DNA. A DNA strand (modelled as a cylinder) is 20 Å in diameter and has a mass of about 2 x 10^6 daltons for each µ m of length. What fraction of the volume of E. coli is DNA? (1 dalton = mass of 1 hydrogen atom, therefore there are 6.025 x 1023 daltons/g).

h2 and H2 compared

Compare h2 and H2. What are the limits of h2 and H2 in determining heritability, specifically in humans?

Analysis of Alleles

1. If a population consists of 122 individuals, how many alleles are present in the population? 2. In the same population of 122 individuals, 25% have the recessive phenotype. a. How many individuals have the recessive phenotype? b. How many alleles are present in individuals with the recessive phenotype?

Taking Advantage of Retrotransposons

In what way may we be able to take advantage of retrotransposons in human gene therapy? How would this differ from our current use of retroviruses?

The Difference Between DNA and RNA

DNA and RNA are similar yet distinct components of the cell. Describe three differences between RNA and DNA with respect to their chemical composition and structure. Provide a detailed description of each characteristic.

Harmful Recessive Traits

1. Perhaps you and/or your significant other is a carrier of a harmful recessive trait, such as cystic fibrosis. What would you do when considering having children? Would you hope for the best and ignore the situation or would you see a genetic counselor or what? 2. Choose a genetic disorder other than those discussed and te

Manipulating the Immune System To Eliminate Cancer Cells Better

Discuss an idea you have about how the immune system/cancer cells could be manipulated so the immune system does a better job at eliminating the cancer cells (it can besomething that you make up based on your understanding of immunology - don't worry if it can't be implemented).

DNA and RNA Analysis

Please help with the following problems. Include at least one reference in the solution. 1) Compare and contrast DNA and RNA 2) Discuss why humans not evolve with one central repository of DNA rather than having it replicated throughout the body?

Genes

Could you please help me with an outline for 3 essay questions? I need a peer-reviewed article and points of interest for each of the following topics: 1. Differential gene expression due to chromosome structure and alternative splicing 2. How genes can be used to possibly lend evidence to the theory of evolution 3. How tec

Costs and Benefits of Genetically Modified Organism Crops

Given what you know about genetically modified organisms (GMOs), identify some of the costs and benefits associated with GMO crops. Which of the costs and benefits do you find most important? Why? Support your response with scientific rationale based on concepts you know.

Genetics and Punnet Squares Problem Set

Single Alleles: Flies can have red or white eyes. Red is dominant to white. 1) Write down letter designations for the alleles. Be sure to distinguish which trait is dominant and which recessive. For example, Mendel used P to designate the purple allele, and p to designate the white allele for pea-flower color. 2) What would

Phenotypic and Genotypic Ratios in Fruit Offspring

In tomatoes, red fruit (R) is dominant to yellow fruit (r). A homozygous red-fruited plant is bred to a yellow-fruited plant. a) What phenotypic ratio would you expect to see in the offspring (F1) of this cross? b) If two of these offspring were bred, what phenotypic ratio would you expect to see in their offspring (F2)

Biological Foundations of Health and Illness

This assignment should be 1-2 pages. Critical Thinking Exercise - Genetic Screening: As we move closer to the day when genetic screening and engineering become commonplace, many scientists are raising concerns about the social, ethical, and political implications of this genetic revolution. Who should decide what const

Genetics and Inheritance of Traits or Genetic Disorders

Part I: Genetics - From Genes to Proteins, Mutations Background: DNA represents the architectural blueprint for all living systems, encoding specific instructions in the sequence of its four nitrogen-containing base pairs that are necessary for building the organism. During the process of transcription, the information in the

Gene Mutations and Disease Expression

There are currently new findings that indicate that mutations outside of genes can cause disease like in Hirshsprung disease and Multiple Endocrine Neoplasia. Explain how this kind of mutation will alter the expression of a gene, particularly in these two diseases. (Answer provided in approximately 150 words.)

Diploid vs. Haploid Example Problem

Why would it be advantageous for an organism to be diploid? Why would it be advantageous for a diploid organism to produce haploid gametes in order to reproduce itself? Why would a geneticist be at a disadvantage studying a diploid organism?

Genetically Modified Organisms

What are the hazards of genetically modified organisms (GMOs)? Is there a solution, or alternative, to having genetically modified foods in our diets?

Mitosis and Meiosis Differences

1. State differences between mitosis and meiosis. 2. List the phases of cell cycle. 3. What is the difference between cell cycle and cell division? 4. State and explain all stages of cell division.

Mitosis & Meiosis

Please identify these questions as true or false. 1. Crossing-over is relatively infrequently between any two genes, but always occurs somewhere during meiosis. 2. Sister Chromatids have identical alleles. 3. Cells that divide by meiosis become haploid after the first division (meiosis I). 4. In humans, the only cell

Gregor Mendel's Laws

I am looking for help with Gregor Mendels laws. With regards to: How do we know that particular human traits are inherited? What did Mendel's finding reveal about inheritance? Explain the answer with the help of the four types of inheritance patterns in pedigrees.

Gregor Mendel and Heritable Factors

Gregor Mendel never saw a gene, yet he concluded that "heritable factors" were responsible for the patterns of inheritance he observed in peas. Similarly, maps of Drosophila chromosomes were conceived by observing the patterns of inheritance of linked traits, not by observing the genes directly. Is it legitimate for biologists t