Four patterns of inheritance and four pedigrees are shown below. Assume that individuals marrying into the family are homozygous for the wild-type allele. Match each of the inheritance patterns with a pedigree.
(a) Autosomal recessive _________
(b) Y-linked trait _________
(c) X-linked recessive _________
(d) Autosomal dominant ______
Please see attachment to view the pedigree choices of inheritance patterns.
An autosomal recessive disease requires two copies of a gene to be present in order for the disease to occur. Thus, both parents would have to be at least carriers in order to develop the disease. Similarly, these disorders can often skip generations, since people with the gene may not express it, but can still pass it on to their children. Therefore, this disease is represented by pedigree II, where two carriers can produce affected children.
A Y-linked trait is passed from ...
The pedigree inheritance patterns are examined. The homozygous for the wild-type alleles are determined.