The galactose represser protein from E. coli has a pI of about 5.9. While purification protocols were being designed, it was found to bind to a Mono-S column at pH values of 7 and below. (Mono-S columns have S-type sulfonic acid groups attached to the resin and are strong cation exchangers.) What is unusual about this observ
Watson and Crick proposed DNA model which helped scientists to understand the chemical structure of DNA. This DNA model was awarded nobel prize in 1953.
What background material did Watson and Crick have available for developing a model of DNA? What was their contribution to the building of the model?
How do amino acid sequences function as a "biological clock?" This process is described.