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Effect of changes in primary structure on nutritional value

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You are a scientist working on a large protein (500 amino acids long) you have genetically engineered the protein in in such a way as to replace a single hydrophobic amino acid with a negatively charged amino acid. How might this substitution alter the primary and the tertiary structure of the protein? How will the nutritional value of the protein change? Make sure you explain the difference between primary and tertiary structures?

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Primary structure refers to the amino acid chain that makes up the protein. It is coded for by the mRNA and formed during translation.

Secondary structure reflects the more complex 3-D structures that a string of amino acid can take. Secondary structures include alpha helices and beta sheets. They are formed by hydrogen bonds and van der Waals forces in regions of the protein.

Tertiary structure is the form the protein takes after all the ...

Solution Summary

Definition of primary, secondary and tertiary protein structure as well as a discussion on the consequences of altering the primary protein structure.

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