Purchase Solution

Gene Mutation Types

Not what you're looking for?

Ask Custom Question

1.
Give a brief description of each of the following:
a.heritable mutation
b.nutritional mutation
c.conditional mutation
2.
a.Write a wild-type DNA sequence with 10 bases and under it write the sequence after a transversion and a transition has occurred. Underline and label both mutations.
b.Write a DNA sequence of 10 bases, and show how a missense mutation results in a mutant sequence. Show the sequence of the transcript and hypothetical amino acid sequence.
c.Repeat part b., but this time show the consequences of a frameshift mutation?
3.
a.Give an example of a spontaneous mutation.
b.Describe what type of mutation results from exposure to UV light.
c.When DNA in a cell undergoes a UV radiation-induced mutation, what are the two possible options for this cell?
4.
Describe an experiment you would do to determine if a food preservative was a mutagen.
5.
a.In a suburb of New York, out of 135,000 people, 64 had a dominant genetic disease; 4 of these individuals had an affected parent. What is the mutation rate for this gene?
b.What does this value mean?

Purchase this Solution

Solution Summary

Short answers with web references for given questions.

Solution Preview

1. Give a brief description of each of the following:
a. heritable mutation
A heritable mutation is a defect which can be passed on from one generation to the next due to a defect in the DNA.
Web reference:
http://biomed.brown.edu/Courses/BIO48/4.Mutants.Link&Recomb.HTML

b. nutritional mutation
Nutritional mutations, also known as auxotraphic mutation, are mutations that interfere with processing of nutrients such as amino acids. For example, a mutation in the gene encoding a protein required for creating arginine in yeast is harmless if yeast are grown on media containing arginine. However, if these yeast are grown on medium lacking arginine they will die.
Web reference:
http://www.faqs.org/health/bios/51/Edward-Lawrie-Tatum.html
http://www.mansfield.ohio-state.edu/~sabedon/biol2015.htm
http://www.ndsu.nodak.edu/instruct/mcclean/plsc431/mutation/mutation4.htm

c. conditional mutation
Conditional mutations are mutations that are only observed under certain conditions. Temperature sensitive mutations are only observed when the temperature is increased or decreased.
Web reference:
http://www.ndsu.nodak.edu/instruct/mcclean/plsc431/mutation/mutation4.htm

2. a. Write a wild-type DNA sequence with 10 bases and under it write the sequence after a transversion and a transition has occurred. Underline and label both mutations.
DNA sequence: ATGCATGCTT
A transversion is a ...

Purchase this Solution


Free BrainMass Quizzes
Infant Development: Sleep

How much do you know about infant sleep? Test your knowledge with this quiz.

The Transfer of Energy in an Ecosystem

This quiz will assess your knowledge of how energy is transferred in an ecosystem and the different levels of trophic organization.

Feeding Babies

Do you know the science behind feeding babies? Test your knowledge with this quiz.

Bacterial Genetics

This quiz test your knowledge of the genetics of bacteria.

Comfort Measures For Labor

Are you ready to doula someone through labor?