Purchase Solution

Gene Mutation Types

Not what you're looking for?

Ask Custom Question

1.
Give a brief description of each of the following:
a.heritable mutation
b.nutritional mutation
c.conditional mutation
2.
a.Write a wild-type DNA sequence with 10 bases and under it write the sequence after a transversion and a transition has occurred. Underline and label both mutations.
b.Write a DNA sequence of 10 bases, and show how a missense mutation results in a mutant sequence. Show the sequence of the transcript and hypothetical amino acid sequence.
c.Repeat part b., but this time show the consequences of a frameshift mutation?
3.
a.Give an example of a spontaneous mutation.
b.Describe what type of mutation results from exposure to UV light.
c.When DNA in a cell undergoes a UV radiation-induced mutation, what are the two possible options for this cell?
4.
Describe an experiment you would do to determine if a food preservative was a mutagen.
5.
a.In a suburb of New York, out of 135,000 people, 64 had a dominant genetic disease; 4 of these individuals had an affected parent. What is the mutation rate for this gene?
b.What does this value mean?

Purchase this Solution
Solution Summary

Short answers with web references for given questions.

Solution Preview

1. Give a brief description of each of the following:
a. heritable mutation
A heritable mutation is a defect which can be passed on from one generation to the next due to a defect in the DNA.
Web reference:
http://biomed.brown.edu/Courses/BIO48/4.Mutants.Link&Recomb.HTML

b. nutritional mutation
Nutritional mutations, also known as auxotraphic mutation, are mutations that interfere with processing of nutrients such as amino acids. For example, a mutation in the gene encoding a protein required for creating arginine in yeast is harmless if yeast are grown on media containing arginine. However, if these yeast are grown on medium lacking arginine they will die.
Web reference:
http://www.faqs.org/health/bios/51/Edward-Lawrie-Tatum.html
http://www.mansfield.ohio-state.edu/~sabedon/biol2015.htm
http://www.ndsu.nodak.edu/instruct/mcclean/plsc431/mutation/mutation4.htm

c. conditional mutation
Conditional mutations are mutations that are only observed under certain conditions. Temperature sensitive mutations are only observed when the temperature is increased or decreased.
Web reference:
http://www.ndsu.nodak.edu/instruct/mcclean/plsc431/mutation/mutation4.htm

2. a. Write a wild-type DNA sequence with 10 bases and under it write the sequence after a transversion and a transition has occurred. Underline and label both mutations.
DNA sequence: ATGCATGCTT
A transversion is a ...

Purchase this Solution
Free BrainMass Quizzes
Nerves and the Nervous System

This quiz will assess your knowledge of the nervous system and how nerves send signals around the body.

Comfort Measures For Labor

Are you ready to doula someone through labor?

Identifying Variables in Science Experiments, Part 2

Using sample experiments, test yourself to see if you can identify independent, dependent, and controlled variables. Identifying variables is key in understanding and developing experiments. The questions are biology related, but this can be applied to any area of science.

Understanding the Musculoskeletal system

Introduce and understand basic information how the skeletal system and muscular system work in close concert with one another. And how their interaction between muscle and bone, as they work together to allow us movement.

Cellular Respiration

This quiz is a review for cellular respiration.

View More Free Quizzes
Related BrainMass Solutions

  • Genetics and Mutations

    One of the mutation may affect expression of the other gene c. One of the mutation may make a gene product that inhibit the other gene product. 7.

  • Health Science - Genetics of Cancer

    Explain how mutations in the same gene can cause different types of cancer. The most direct answer to this question is to consider that each cell type in the body is under its own set of gene regulatory molecules.

  • Molecular Biology - Multiple Choice

    The DNA sequence of a codon in a gene was changed from AAT to AAC. This type of mutation is called a(n) __________. a. point mutation b. insertion mutation c. deletion mutation 3.

  • Types of Gene Mutations for Genetics Students

    461510 Gene Mutations (Base Substitutions, Insertion & Deletion) Discuss the three different types of gene mutations (base substitutions, insertion & deletion).

  • DNA Mutation Sequences and Their Impact on DNA replication

    These diseases are caused by the mutation of a single gene. Most inherited genetic diseases are recessive, which means that a person must inherit two copies of the mutated gene to inherit a disorder. 3.

  • Explaining prevalent mutations in a small and large population

    There are several types of mutations, both at the gene-level and the chromosome-level. Gene mutations provide new alleles, making these mutations the ultimate source of variation.

  • Genetics and Population Biology

    A mutation is actually a change in one or two alleles of a single gene. There are several types of mutation. Point mutation is when one base is deleted on the DNA that can cause a phenotypic change in the gene.

  • Prokaryotic Genetic Recombination and Types of Operons

    Mutation can have varied effects on the gene expression and subsequent bacterial metabolism depending upon the type of mutation and the target genes. For example, mutation in the promoter can prevent the whole of the operon from expressing itself.

  • The CF gene

    342940 The CF Gene - Randomness and Mutation Why do you think another mistake doesn't just correct the mutation in an abnormal CF gene?

  • Genetics and Personalized Medicine

    The point mutation is the smallest mutations in which a singe base pair is changed into another base pair. There are many different types of mutation. Mutations that change a single base pair into another base pair is called a point mutation.

View More Related Solutions