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DNA frame-shift

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Frame-shift mutations occur when a nucleotide is accidentally omitted or added to DNA. Would a frame-shift mutation be more harmful if it occurred at the start of a gene or near the end of the gene? Why?

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Solution Summary

Brief explanation of what a frame-shift mutation is and the consequences it has on protein translation.

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Frame-shifts caused by insertion or deletion of nucleotides often result in premature termination protein translation. This is most serious when the frame shift ...

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