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Chromatography

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How do you determine an instrument's (hplc or gc) detection sensitivity? How do you determine the detector's limit of detection (LOD) and limit of quantitation (LOQ)?

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Detection sensitivity
Q. How to determine an instrument's (hplc or gc) detection sensitivity? And how to determine detector's limit of detection (LOD) and limit of quantitation (LOQ)?

A. Maximum sensitivity means we will be able to detect smaller changes in concentration.
GC's are equipped with flame ionization detectors (FID), Mass Spectrometry (MS) detectors or thermal conductivity detectors (TCD). FID's provide the best ...

Solution Summary

This 229 word solution offers concise answers to some questions related to the sensitivity of chromatographic measurements and includes a complete list of source references.

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