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    Column Chromatography Questions

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    -Why is a layer of sand above the alumina in the column in column chromatography?

    - What are the differences between column chromatography and thin layer chromatography?

    - If a compound had an Rf value of .5 in a particular solvent, how many column lengths of that solvent would it theoretically require for the compound to travel through the column.

    -Explain why or why not NaCl can be purified by column chromatography.

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    Solution Preview

    -Why is a layer of sand above the alumina in the column in column chromatography?

    It is customary to apply the compound to the top of the column with very little solvent on top. Sand can the be placed on top of the column. This prevents the compound on top of the column from being disturbed when solvent is added to the column. This ensures a more even separation.

    - What are the differences between column chromatography and thin layer chromatography? ...

    Solution Summary

    Aspects of column chromatography and thin layer chromatography are discussed.

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