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Molecular Motors and Models.

See attached 5 questions (related to each other) on molecular motors. I have trouble drawing the model and doing the calculations.

1. The attached table is from the notes. Show that 1 kCal/mOl =418.7 CEU (see attachment for the table).

2. Molecular motors typically generate forces in the range of a few piconewtons. Suppose a motor generates a force of 1 pN. How much work is done when this motor moves a load through a distance of 3.4A? Note that work = force*distance, and that 3.4A is the distance between two successive base pairs in double-helical DNA. (Express your answer in Joules).

3. To get some idea of how large the work in problem 1 is in macroscopic terms, suppose that one mole of motors each moves a load through a distance of 3.4A with a force of 1 pN. How much total work is done? (Express your answer in kcal/mol).

4. Draw the tripeptide tyr-ala-asp. Show all hydrogen atoms. Be sure to show the correct ionization states of all ionizable atoms at pH 7.

5. Draw the trinucleotide C-A-G at pH 7. (lnclude a phosphate group on the 5'-end but not
on the 3'-end). Show all hydrogen atoms. Be sure to show the correct ionization states of all ionizable atoms at pH 7.

Please see the attachment for the complete question.

Attachments

Solution Preview

The solution is attached below in two files. the files are identical in content, only differ in format. The first is in MS Word format, while the other is in Adobe pdf format. Therefore you can choose the format that is most suitable to you.

Converting units is simply successively multiplying the original value by "1" making sure the required units cancel out.
For example, note that since we can write
And when we multiply by the calorie unit ...

Solution Summary

The molecular motors and models are examined in the solution.

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