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Koch's Postulates and Molecular Genetics

I understand that Koch's postulates have limitations, but I don't understand how that plays a role in molecular genetics.

Here is my question.

Given the limitations of Koch's postulates, what role do you see for molecular genetics and associated techniques in addressing the exceptions to the postulates?

Solution Preview

Koch's postulates are as follows:
1. The microorganism must be found in abundance in all organisms suffering from the disease, but not in healthy organisms.
2. The microorganism must be isolated from a diseased organism and grown in pure culture.
3. The cultured microorganism should cause disease when introduced into a healthy organism.
4. The microorganism must be re-isolated from the inoculated, diseased experimental host ...

Solution Summary

Several paragraphs examining Koch's postulates, their limitations and the role of molecular genetics in addressing these limitations.