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RNA polymerases during Replication or Transcription

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Discuss why RNA polymerases are not able to correct base errors during replication or transcription. Describe the biological consequences of the protein that may develop in this case.

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Genetic damage may occur during transcription resulting in a block polymerase action. This results in the creation of a signal for DNA repair machinery to move in and correct the mistake. When polymerases are not blocked, however, non-dividing cells can continue the work of transcription, all the while reading an erroneous coding message. This base substitution error has very important implications for the biological consequences of genetic damage in non-dividing ...

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The solution is a detailed discussion of RNA polymerase in replication and transcription. The solution is 284 words.

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