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A review of clonal selection in immunology

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What is clonal selection in relation to the immune system and lymphocytes? What is the significance of clonal selection?

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This solution provides a detailed explanation of the given biology questions regarding the human immune system.

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Clonal selection is one of the most powerful tools in the armoury of the immune system. Any single lymphocyte (B or T cell) expresses receptors with a single specificity, and at any given time there will be millions of lymphocytes with millions of different specificities in your body. These lymphocytes remain inactive (naà¯ve), until their receptors are engaged by an appropriate antigen under the correct conditions of lymphocyte stimulation (such as ...

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