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Neurotransmitter effects on Schizophrenia and Depression

This solution describes how the major neurotransmitters dopamine, serotonin, and norepinephrine effect schizophrenia and major depression. It describes the positive, negative, and cognitive symptoms of schizophrenia and how the new atypical antipsychotic medication Ariprazole is a very helpful partial agonist in treating schizophrenia. It also discusses how serotonin and norepinephrine act on the synapses in major depression, and how the serotonin and norepinephrine reuptake inhibitors (SNRIs) are used to treat major depression. The parts of the brain involved in schizophrenia and depression are mentioned as well.

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What are the primary neurotransmitters? What role do they play in brain function and behavior?

In schizophrenia, dopamine is the major neurotransmitter involved, and its behavioral role and the parts of the brain involved can be described via the positive, negative, and cognitive symptoms found in schizophrenia. The positive symptoms of this disease (i.e. thought disorders, hallucinations, and delusions of grandeur, persecution, and control) are thought to be "caused by overactivity of synapses between dopaminergic neurons in the nucleus accumbens and amygdala" (Carlson, 2010, p. 558). The ...

Solution Summary

This solution describes how the major neurotransmitters dopamine, serotonin, and norepinephrine effect schizophrenia and major depression. It describes the positive, negative, and cognitive symptoms of schizophrenia. It also discusses how serotonin and norepinephrine act on the synapses in major depression, and how the serotonin and norepinephrine reuptake inhibitors (SNRIs) are used to treat major depression. The parts of the brain involved in schizophrenia and depression are mentioned as well.

Reference

Carlson, N.R. (2010). Physiology of behavior. (10th ed.) Boston, MA: Pearson/Allyn and Bacon.

This solution provides descriptions of how the neurotransmitters dopamine, serotonin, and norepinephrine effect schizophrenia and major depression. It also mentions the areas of the brain involved in these diseases, the positive, negative, and cognitive symptoms of schizophrenia, atypical antipsychotics, and how the serotonin and norepinephrine reuptake inhibitors (SNRIs) act on the synapses in treating major depression.

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