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Discussion on various endocrinology questions.

This solution discusses four endocrinology questions:

1. List the four mechanisms involved in the regulation of aldosterone secretion.

2. Mr. Sanchez makes an appointment to see his doctor for pain in his abdominal area. Tests and x-rays reveal kidney stones as well as bones with a moth-eaten appearance. Further questioning reveals a medical history of abnormal reflexes and weakness. What is the problem and what treatment would be recommended?

3. It was often rumored that one of our deceased presidents was suffering from Addison's disease (inadequate synthesis of mineralocorticoids and glucocorticoids). What symptoms may have led to the diagnosis of this condition?

4. John is a 26-year old man who begins to notice a progressive enlargement of feet, hands, cranium, nose and lower jaw bone. His doctor recommends irradiation of the pituitary gland. What is the most likely diagnosis? Why?

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1. List the four mechanisms involved in the regulation of aldosterone secretion.

Renin-angiotensin pathway
Blood K+ levels (inc. = stimulation; dec. = suppression)
ACTH
Baroreceptors (inc pressure in carotid artery = suppression)

2. Mr. Sanchez makes an appointment to see his doctor for pain in his abdominal area. Tests and x-rays reveal kidney stones as well as bones with a moth-eaten appearance. Further questioning reveals a medical history of abnormal ...

Solution Summary

This solution discusses four endocrinology questions:

1. List the four mechanisms involved in the regulation of aldosterone secretion.

2. Mr. Sanchez makes an appointment to see his doctor for pain in his abdominal area. Tests and x-rays reveal kidney stones as well as bones with a moth-eaten appearance. Further questioning reveals a medical history of abnormal reflexes and weakness. What is the problem and what treatment would be recommended?

3. It was often rumored that one of our deceased presidents was suffering from Addison's disease (inadequate synthesis of mineralocorticoids and glucocorticoids). What symptoms may have led to the diagnosis of this condition?

4. John is a 26-year old man who begins to notice a progressive enlargement of feet, hands, cranium, nose and lower jaw bone. His doctor recommends irradiation of the pituitary gland. What is the most likely diagnosis? Why?

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