Purchase Solution

Generation of Diversity Purpose

Not what you're looking for?

Ask Custom Question

Explain the purpose (and briefly the method) of generating a TCR transgenic mouse ? Why TCR transgenic mice are often made on a rag-/- background ?

Purchase this Solution

Solution Summary

The generation of diversity purposes are determined. The expert explains the purpose of generating a TCR transgenic mouse.

Solution Preview

The purpose of generating a TCR transgenic mouse is to generate a mouse with a population of T-cells sharing a single TCR specificity. This is done by cloning the desired already-rearranged TCR genes (TCR is composed of 2 peptides encoded by 2 distinct genes). Mice expressing these cloned TCR ...

Purchase this Solution


Free BrainMass Quizzes
Feeding Babies

Do you know the science behind feeding babies? Test your knowledge with this quiz.

The Transfer of Energy in an Ecosystem

This quiz will assess your knowledge of how energy is transferred in an ecosystem and the different levels of trophic organization.

Vision and Oculomotor Control

This quiz will test the student's knowledge of the neural underpinnings of the visual system and its central pathways.

Basic Immunology Quiz

Intro to immuno quiz. Covers the basics of immunology and recognition of foreign substances by the body.

Hemophilia: Fact or Fiction

Do you know the truth about hemophilia? Test your knowledge here.