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Genetic Disorders

3. Explain why teratogens are difficult to identify.

4. Explain why a woman carrying the gene for hemophilia can produce two hemophiliac sons when she is mated to a normal male.

5. Under what conditions does a female acquire an X-linked recessive disorder?

7. The pedigree for Queen Victoria of England, a carrier of hemophilia A, shows the transmission to some of her descendants, including members of many royal families in Europe, such as Russia and Spain, but not Germany. Hemophilia A does not affect anyone in the present British royal family. Can you explain why hemophilia A has disappeared from one family and appeared in others?

11. Which of the following can be identified by an abnormal karyotype?

a. Sickle cell disease
b. Cystic fibrosis
c. Monosomy X
d. Tay-Sachs disease
e. Huntington's disease

Solution Preview

EFFECTS OF ALTERED STATUS/GROWTH AND DEVELOPMENT ON DISEASE PROCESSES
3. EXPLAIN WHY TERATOGENS ARE DIFFICULT TO IDENTIFY.

Teratogens are substances which disrupt the developmental pattern of an embryo. Below are some of the reasons why teratogens are hard to identify
? the teratogen's ability to alter normal developmental processes
? the susceptibility of the target tissue (timing of fetal exposure)
? the concentration of teratogen required to illicit an effect
? genetic make-up of the individuals (mother and fetus) involved (host resistance)

4. EXPLAIN WHY A WOMAN CARRYING THE GENE FOR HEMOPHILIA CAN PRODUCE TWO HEMOPHILIAC SONS WHEN SHE ...

Solution Summary

The solution talks about why teratogens are hard to identify and what the consequences of an X-linked recessive disease like Hemophilia mean for the Royal Family.

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