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DNA cloning and genetic disease

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8. Explain how information of the sequence of cloned genes can shed light on the function of their coding genes.

9. Explain how PCR can be used in the diagnosis of a genetic disease.

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8. The sequence of a cloned gene can shed information on its function because the DNA sequence can be converted into the RNA then protein sequence. This primary protein sequence can then be analyzed to find conserved domains or similarities with other proteins and thus reveal possible function. If the gene encodes a protein that has a ...

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