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Pathway of Atoms in Gluconeogenesis

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A liver extract capable of carrying out all the normal metabolic reactions of the liver is briefly incubated in separate experiments with the following 14C-labeled precursors (see attached). Trace the pathway of each precursor through gluconeogenesis. Indicate the location of 14C in all intermediates and in the product, glucose.

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Solution shows all intermediate steps and final outcome for the transformation in attached .jpg file.

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a) If you follow the pyruvate carboxylase reaction, in the first step 14CO2 is added ...

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