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NMDA receptors and mammalian neurons

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Would you expect ALL mammalian neurons to have functional NMDA receptors? Please explain your answers.

I am looking for any feedback you can provide. I am happy to receive any feedback you may offer on this topic. Thanks much!

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Would you expect ALL mammalian neurons to have functional NMDA receptors? Please explain your answers.

This question is asking your opinion so you can answer either affirmatively or negatively, however you need to support your opinion with facts.

The facts:

What are NMDA receptors: One of four receptors for the excitatory neurotransmitter glutamate. The others are AMPA and kainite (also ionotropic) receptors and one metabotropic receptor. While AMPA and kainite are responsible for fast, often transient excitatory action potentials (EPSP), NMDA receptors are responsible for long lasting, slower responses. They, along with AMPA, are ...

Solution Summary

In this solution I define NMDA receptors (as well as other glutamate receptors), where they are found and what they do, giving enough information to allow the user to formulate an opinion about whether to expect all mammal neurons to have functional NMDA receptors.

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Neuron Bathed in Muscimol & Baclofen

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Plate 1 shows the normal activity of a neuron. Plate 2 shows the activity of a neuron after being bathed in muscimol (a GABAa agonist). Plate 3 shows the activity of a neuron after being bathed in balcofen (a GABAb agonist). Plate 4 shows the wash out of drugs. Explain this figure (i.e. what is happening at the synapse? Why is one type of GABA agonist more effective than the other? Explain how each receptor functions to affect synaptic activity.

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