I am looking for a lab protocol on synthesizing sulfathiazole from p-acetamidobenzenesulfonyl chloride and 2-aminothiazole. It would be appreciated if exact amounts of reagents, solvents, etc (in grams, mmols, mls - etc), could be given.
Regarding thesynthesis of sulfathiazole from 2-aminothiazole and p-acetamidobenzenesulfonyl chloride, I would like balanced equations for each step, i.e. forthe initial reaction resulting in the intermediate and the subsequent hydrolysis step resulting in the actual product, i.e. sulfathiazole.
Note: I did not use pyridine
Answer the following questions concerning sulfathiazole, below.
What is the hybridization of the nitrogen atom in sulfathiazole?
Assuming that the sulfur atom is sp2-hybridized, how many -electrons are there in thesulfathiazole ring?
What reactivity do you predict forsulfathiazole?
I need some help with answering these questions: (See attached file for full problem description and structural formulas)
1. Predict whether the molecule would be expected to show aromatic character or not. Explain your answer.
2. What is the hybridization of the nitrogen atom in sulfathiazole?
3. Assuming that the sulfur
Metabolism uses various ways to ensure that 2 opposing pathways do not occur at the same time. Forthe following pair of pathways list 2 ways (different cell location, allosteric effector, covalent modification, different intermediate, different enzyme, or different means of transport).
How are fatty acid oxidation and fat
A.) Write a complete mechanism forthe addition of diethyl malonate to ethanal in the presence of base to form a beta-hydroxy ester.
B.) Outline a sythensis that forms at least on C - C bond for each of the following compounds: