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    Liquid Chromatography: Capacity, Selectivity and Resolution

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    Based on Liquid Chromatography, how can I changed if the capacity value and selectivity value and resolution value is not in the proper range?

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    https://brainmass.com/chemistry/environmental-chemistry/liquid-chromatography-capacity-selectivity-resolution-579305

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    See the attached file.

    LC parameters
    Based on LC, how can I changed if the capacity value and selectivity value and resolution value is not in the proper range?

    Although the selectivity factor, , describes the separation of band centers, it does not take into account peak widths. Another measure of how well species have been separated is provided by measurement of the resolution. The resolution of two species, A and B, is defined as

    Baseline resolution is achieved when R = 1.5
    It is useful to relate the resolution to the number of plates in the column, the selectivity factor and the retention factors of the two solutes;

    To obtain high resolution, the three terms must be maximized. An increase in N, ...

    Solution Summary

    This solution clearly highlights the answers in bold and explains the rationale behind in a easily understandable manner with step-by-step calculations, aided with some references.

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