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Immune response in the outcome of schistosomiasis

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The type of T cell-mediated immune response has a key impact on the outcome of several parasite infections. This solution uses schistosomiasis as an example to explain how different types of T cell response can have different effects on the control of the parasite.

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This solution explains how different types of cellular immune response can influence the outcome of infection with the schistosome parasite.

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Disease caused by schistosome infection is largely the result of an immune response to the parasite, rather than cell destruction caused by the parasite itself. During chronic infection, granulomas form in response to parasite eggs in the liver and intestine, causing fibrosis and hypertension that is responsible for much of the severe disease seen with this infection. The reason ...

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