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Signs of Preicteric and Icteric Stages of Acute Hepatitis

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A 40-year-old man has chronic hepatitis B. What may be the cause of his condition? Describe the pathophysiology of hepatitis B.

What are the signs of preicteric and icteric stages of acute hepatitis?

What serum markers are found?

Is cirrhosis likely to develop and what pathophysiological changes are taking place?

If the patient developed ascites, edema, esophageal varices, or respiratory infections, what might be happening?

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Solution Summary

This solution carefully demonstrates the pathophysiology of hepatitis B.

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Hi,

Hepatitis can cause a range of liver problems including acute hepatitis, chronic hepatitis, cirrhosis and hepatocellular carcinoma. In most of the cases Hep B leads to only acute hepatitis which may or may not be symptomatic. In 5-10% of the individuals it progresses to chronic infection. The following article gives you the detail on pathogenesis of Hepatitis B viral Infection that is summarized below .

Chisari eta l. 2010
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888709/?tool=pubmed

Viral hepatitis is a necroinflammatory disease and involves human immune response to cause cytological abnormalities and inflammation. Virus is in itself shown to be incapable of causing the cytopathic effect. Hepatitis B virus evades the ...

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