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Mechanism of action of chemotherapeutic drugs

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Two examples of chemotherapeutic drugs and their cellular actions are listed below. Explain why each drug could be fatal to a cell.

Vincristine: Damages the mitotic spindle.

Adriamycin: Bind to DNA and blocks mRNA synthesis

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Solution Summary

This solution addresses the mode of action of two commonly used chemotherapeutic anti-cancer drugs.

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Chemotherapeutic drugs often target basic cellular processes that are greatly enhanced in tumor cells, in an effort to kill these cells. Vincristine damages the mitotic spindle. making it impossible for the mitotic chromosomes to segregate into ...

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