pathophysiology of atherosclerosis
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Please help with the following problem regarding atherosclerosis.
A clear and concise description of the pathophysiology of atherosclerosis from the perspective of the role of the endothelial wall. Includes a list of risk factors, known and emerging, for atherosclerosis
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Solution Summary
This solution examines the pathophysiology of atherosclerosis and explains the role of the endothelial wall and includes a list of risk factors for atherosclerosis.
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Pathophysiology of atherosclerosis:
The endothelial lining has multiple protective functions, the pathophysiology of atherosclerosis causes a breakdown in these functions.
FUNCTIONS OF THE ENDOTHELIUM:
a) barrier
b) antithrombotic
c) vascular tone, vasodilation
d) prevent smooth muscle migration
e) immune functions (binds leukocytes when injury)
development of atherosclerosis:
1) Injury occurs! 2 types of injury:
a) Physical forces (more common at branch points due to turbulence)
b) Toxic chemical environment (cigarettesà reactive 02 species: superoxides; ...
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