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Aspects of Muscle Contractions

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Please summarize the following concepts to help me study for my exam:

1) Compare the action of a neuromuscular junction with that of a typical neuroneural chemical synapse.
2) Mechanism of excitation-contraction coupling
3) Sources of ATP for muscle contraction
4) Isometric and isotonic contraction

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The solution involves discusion of the neuromuscular junction compared to a typical neuroneural chemical synapse, the mechanism of excitation-contraction coupling, sources of ATP for muscle contraction and isometric and isotonic contractions.

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1) Compare the action of a neuromuscular junction with that of a typical neuroneural chemical synapse.

The neuromuscular junction works very similar to a typical neuro-neuronal synapse in that (a) the electronic impulse arrives at the nerve ending in the muscle, (b) initiating the release by the vesicles of a chemical transmitter that diffuses across the union, (c) those chemicals then dock or unite to the receptor sites in the muscle membrane, (d) increasing the release of sodium in the membrane and turning the membrane potential less negative reaching the threshold potential. An impulse will travel across the muscle causing a contraction when the action potential is created (Ritchinson, 2008). This mechanism is true for the skeletal muscle.

2) Mechanism of excitation-contraction coupling
The mechanism of ...

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