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    Working in a research lab, a colleague has identified an mRNA strand that can be translated into a particular protein.
    Your job is to decode the DNA that would be transcribed to form the mRNA strand in question. Given the mRNA strand below, label the sense and anti-sense strands of the DNA you decode. EXPLAIN the observations and the inferences that help to decide which strand is which.

    A U G U A U G A G A A U C C C C G G U A A

    This job is decoded.

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    The messenger RNA (mRNA) is transcribed from the DNA template by an RNA transcriptase. As you are aware, DNA is comprised of two helical strands linked together by the hydrogen bonds between the nucleoside bases attached to the phosphate backbone. See figure 1:

    Figure 1. The familiar Rosalind Franklin, James Watson, Francis Crick and Maurice Wilkins model of the DNA molecule (all but Dr. Franklin received the Nobel Prize in 1962 for this work). The graphical representation of the double helix structure of DNA is from Molecular Biology of the Cell, 3rd edition, Alberts et al., 1994

    The mRNA molecule will represent exactly the sequence of the plus strand of the gene (with the U- uracil in RNA replaced by T- thymine in the DNA), if ...

    Solution Summary

    Help with a DNA strand is given.