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Antibody/antigen binding

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Explain why an antibody could sometime bind differently to an antigen in function of its native or denatured conformation.

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Solution Summary

An explanation of how antibodies and antigens interact along with web links.

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The reason an antibody would have different binding to an antigen in its native and denatured form has to do with the nature of proteins. Antibodies are proteins and like any other protein their properties (like binding other proteins) depend on their three dimensional structure. Proteins are composed of a string of amino acids. These amino acids can interact with other amino acids in different parts of the protein through ...

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