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    Advanced physiology

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    1) A 22- year old man was in a motorcycle accident with resultant neck injuries that led to partial paralysis of the upper and lower limbs. Almost immediately his chest felt heavy and he became dyspneic. His pulmonary values:

    Vital capacity (supine) = 650 ml
    Minute ventilation (supine) = 6 L/min
    Respiratory rate (supine) = 30 b/min
    PaO2 = 61 mmHg
    PaCO2 = 47 mmHg

    a)What nerves and muscles are involved in this case?
    b)What is causing significantly reduced alveolar ventilation?

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    Solution Preview

    a) The respiratory rate is controlled by the respiratory centre in the medulla oblongata in the brain. In this case, there has been damage to both his intercostal nerve branch and his phrenic nerve branch. As a consequence there ...