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Standard Genetic Code

Using the standard genetic code, interpret the following
a) The following sequence was found to occur on a mRNA molecule:
5'-CCUUACACAGGAAACACGUAUGACCAUUGAGGCUUGAACAA-3'
What amino acid sequence is represented here following its translation?

b) For the above mRNA sequence, identify the bases that correspond to the Shine-Dalgarno sequence. Explain your answers.

c) Describe how the amino acid sequence would change if the twenty-first base (U) were mutated to G.

Solution Preview

a) The following sequence was found to occur on a mRNA molecule:

5'-CCUUACACAGGAAACACGUAUGACCAUUGAGGCUUGAACAA-3'

What amino acid sequence is represented here following its translation?

Response:

Let us separate the sequence into triplets to help us see it better.

5'-CCU UAC ACA GGA AAC ACG UAU GAC CAU UGA GGC UUG AAC AA

Since this is mRNA, to obtain the amino acid sequence, all we have to do is look up the triplet codons on the genetic code table. You could go to http://img.sparknotes.com/figures/1/132e5720f3b37836571a1aeb9d163ac3/genetic_code.gif for one.

Here would be a start for determining the amino acid sequence:

Proline - Tyrosine - Threonine - Glycine - Asparagine - Tyrosine - etc...

b) ...

Solution Summary

The expert examines standard genetic code interpreting. An mRNA sequence is examined.

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