Primase is the enzyme responsible for:
a. unwinding the DNA double strand to allow DNA polymerase access to the template DNA
b. introducing nicks into the DNA double strand in order to prevent the formation of knots
c. hydrolyzing ATP to facilitate DNA unwinding
d. making short strands of RNA at the site of replication initiation
e. forming a replication fork in the DNA double helix
This solution helps go through primase activation within the context of cell and molecular biology.