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Down Syndrome

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Is it possible for two people who have Down syndrome to give birth to a normal (without Down syndrome) child? If so, how would that be possible?

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Solution Summary

This solution explores the possibility of two people who have Down syndrome to give birth to a child without Down syndrome.

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Yes. Down syndrome is caused by the presence of an extra chromosome 21 (or an extra part of that chromosome).

In this situation, both the mother and father have Down syndrome. In the process of meiosis (the formation of sperm or egg cells), the number of chromosomes per cell are divided in half. Let's look at how this would affect meiosis in the mother:

(1) Original cell: 3 copies of chromosome 21
(2) DNA replicates: 3 copies of ...

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