Purchase Solution

protein that has two transmembrane domains

Not what you're looking for?

Ask Custom Question

I am studying a protein that has two transmembrane domains. The spacing of the transmembrane domains is show as boxes on figure below. The C-terminal domain of the protein is cytoplasmic. Is the N-terminal domain of the protein cytoplasmic or extracellular? Why? Which portion of the protein will be most likely to be glycosilated.

NB: I attached a figure show transmembrane domains.

Attachments
Purchase this Solution
Solution Summary

This job assesses a protein that has two transmembrane domains.

Solution Preview

Hello and thank you for posting your question to Brainmass.

The N terminus of the protein is cytoplasmic.

Note that we talk about trans-membrane domains, which means each domain spans the entire membrane (unlike for example the p-loop in ion channels that ...

Purchase this Solution
Free BrainMass Quizzes
Nerves and the Nervous System

This quiz will assess your knowledge of the nervous system and how nerves send signals around the body.

Pregnancy Knowledge

How much do you know about being pregnant? Test your Pregnancy IQ with this quiz!

The Heart

This quiz test the understanding of the heart and some of its parts. It is important to understand how the heart functions and what makes it function.

How Much Do You Know About Genetic Inheritance?

Most of us studied the basics of dominant and recessive genes at some point. However, genetics are much more complicated than this. How far beyond the basics does your knowledge go?

Understanding the Musculoskeletal system

Introduce and understand basic information how the skeletal system and muscular system work in close concert with one another. And how their interaction between muscle and bone, as they work together to allow us movement.

View More Free Quizzes
Related BrainMass Solutions

  • Protein translation and the ER

    Describe what type of ER targeting signal sequences each of the following proteins would need for proper translation and localization: A) A protein that functions in the lumen of the ER B) An integral membrane protein with 3 membrane spanning domains

  • Literature Review: Cadherin-mediated cell-cell adhesion.

    It has been further documented that additional proteins can be co-precipitated with the soluble or extracellular fraction of the E-cadherin protein.

  • Effect of changes in primary structure on nutritional value

    Hydrophobic amino acids are often found in the secondary structures necessary to form transmembrane domains.

  • Integrin and Extracellular matrix

    The "α subunit is made initially as single 140K Dalton polypeptide chain, which is then cleaved into one small transmembrane domain, and one large extracellular domain that contain four divalent cation binding sites." (1) The two domains are held together

  • BIOCHEM GRE Subject Question

    36058 Thickness of a Membrane You have been investigating a membrane protein that appears to have seven 24 residue transmembrane Alpha helices.

  • Cell to Cell Contact Computing

    Cell-cell contact at these junctions is mediated by the protein occludin.

  • Compartments in the secretory pathway

    I realize that my explanation is a bit broad here, so do not hesitate to let me know if I can help with this question more! With regard to protein targeting, the distinction between the two is WHEN they occur.

  • G-Protein Signalling Events

    That said it will be of importance to note that α2 receptors result in constriction and β receptors result in relaxation of the SMC. Both α2 and β are G-protein receptors with 7 transmembrane domains and three subunits (αβγ).

  • Western blot analysis

    When protease is added to the mix only the portion of the protein that has entered the microsome will be protected.

View More Related Solutions