I am studying a protein that has two transmembrane domains. The spacing of the transmembrane domains is show as boxes on figure below. The C-terminal domain of the protein is cytoplasmic. Is the N-terminal domain of the protein cytoplasmic or extracellular? Why? Which portion of the protein will be most likely to be glycosilated.
NB: I attached a figure show transmembrane domains.© BrainMass Inc. brainmass.com October 2, 2020, 12:00 am ad1c9bdddf
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The N terminus of the protein is cytoplasmic.
Note that we talk about trans-membrane domains, which means each domain spans the entire membrane (unlike for example the p-loop in ion channels that ...
This job assesses a protein that has two transmembrane domains.