Consider the isomerization reaction between glucose-6-phosphate and fructose-6-phosphate.
a) What is the ratio of fructose-6-phosphate to glucose-6-phosphate under standard conditions?
b) Under typical cellular conditions, the steady state concentrations of glucose-6-phosphate and fructose-6-phosphate are 0.083mM and 0.014mM. What is delta G' under cellular conditions?
c) In what direction does the reaction proceed under cellular conditions?
a) Looking up in a table, I can see that for this reaction, G6P ------> F6P
dG' = 0.40 kcal/mol
This is at standard conditions, pH 7.0 and 25 degrees C.
I'm assuming that the first question should be, "What is the equilibrium ratio under standard conditions?" -- the important point being ...
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