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    Isomerization Reaction Ratio

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    Consider the isomerization reaction between glucose-6-phosphate and fructose-6-phosphate.
    a) What is the ratio of fructose-6-phosphate to glucose-6-phosphate under standard conditions?
    b) Under typical cellular conditions, the steady state concentrations of glucose-6-phosphate and fructose-6-phosphate are 0.083mM and 0.014mM. What is delta G' under cellular conditions?
    c) In what direction does the reaction proceed under cellular conditions?

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    a) Looking up in a table, I can see that for this reaction, G6P ------> F6P
    dG' = 0.40 kcal/mol
    This is at standard conditions, pH 7.0 and 25 degrees C.

    I'm assuming that the first question should be, "What is the equilibrium ratio under standard conditions?" -- the important point being ...

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    This solution includes calculations, answers and explanation. 210 words.