Purchase Solution

Human Hemoglobin Sample

Not what you're looking for?

Ask Custom Question

Normal Human Hemoglobin (HbA) P50 = 26 torr and the hill coefficientis N= 2.8

You have obtained the following oxygen binding curve data on a new sample of human hemoglobin.

A) Is this sample normal?

(This can be solved by visual inspection)

po2 log(po2) Theta theta/1-Theta) Log(theta/1-Theta)
10 1.000 0.0039 0.0039 -2.4089
20 1.301 0.0588 0.0625 -1.2041
30 1.477 0.2404 0.3164 -0.4998
40 1.602 0.5 1.0000 0.0000
50 1.699 0.7094 2.4410 0.3876
60 1.778 0.8351 5.0630 0.7044
70 1.845 0.9037 9.3790 0.9722
80 1.903 0.9412 16.0000 1.2041
90 1.954 0.9624 25.6300 1.4087
100 2.000 0.975 39.0600 1.5917

Attachments
Purchase this Solution

Solution Summary

This solution is provided in 224 words. It discusses the importance of P50 and Hill coefficient values in determining if a sample of hemoglobin is normal or not.

Solution Preview

To answer this problem, you need to figure out the values of P50 and n (the Hill coefficient) for the new hemoglobin sample, then compare these to the values for normal hemoglobin.

P50 describes the partial pressure of oxygen at which half of the O2 binding sites are occupied. Theta represents the fraction ...

Purchase this Solution


Free BrainMass Quizzes
Human Anatomy- Reproductive System

Do you know your reproductive anatomy?

Breastfeeding Basics

How much do you know about breastfeeding? Find out with this quiz!

Basic Immunology Quiz

Intro to immuno quiz. Covers the basics of immunology and recognition of foreign substances by the body.

The Heart

This quiz test the understanding of the heart and some of its parts. It is important to understand how the heart functions and what makes it function.

Do You Know Your Macromolecules?

This quiz will assess your knowledge of the macromolecules that are important to living things.