Title:New technology prevents breast cancer development in transgenic mice.
Source:Women's Health Weekly (Nov 18, 2004): p.140. (183 words) From General OneFile.
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Full Text :COPYRIGHT 2004 NewsRX
2004 NOV 18 - (NewsRx.com & NewsRx.net) -- Parker Hughes scientists announced that they have developed a new technology capable of preventing the development of breast cancer in mice.
Results from these research studies will be published in two papers in the November issue of the international medical journal Arzneimittelforschung (Drug Research). In the studies Parker Hughes scientists found that a novel cytotoxic nucleoside analog, compound 003 (3'-Azidothymidine 5' - p-Methoxyphenyl methoxyalaninyl phospate), was well tolerated in both mice and rats without toxicity. Most notably, the scientists said that compound 003 prolonged cancer-free survival in transgenic mice, without any significant side effects and at dose levels much lower than those found to be safe in animals. These transgenic mice invariably develop HER2 positive metastatic breast cancer.
An estimated 216,000 women will be diagnosed with breast cancer this year. Women with HER2 positive breast cancer have a greater risk for recurrence of their breast cancer and an increased risk of mortality.
This article was prepared by Women's Health Weekly editors from staff and other reports. Copyright 2004, Women's Health Weekly via NewsRx.com & NewsRx.net.
Source Citation:"New technology prevents breast cancer development in transgenic mice." Women's Health Weekly (Nov 18, 2004): 140. General OneFile. Gale. Apollo Library. 26 Mar. 2008
Gale Document Number:A124589247
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