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Organic Synthesis Mechanism

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1. Draw the product structure in this experiment:
See attached file for full problem description.

2. Draw and explain the detailed mechanism for the Biginelli Reaction performed in this experiment:

3. Nifedipine exerts a potent vasodilatory effect on both coronary and peripheral
vasculatures. Compare the structure of the Biginelli product and of Nifedipine in terms of their structure-activity relationships.

See attached file for full problem description.

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Solution Summary

Bignelli Reaction mechanism in detail is explained along with explantion on structure activity relationships of Bignelli product and Nifedipine.

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