Explore BrainMass
Share

Friedel-Crafts Alkylation and Acylation, Nitration

This content was STOLEN from BrainMass.com - View the original, and get the already-completed solution here!

Please see the attached file for the fully formatted problems.

1. When performing a Friedel-Crafts alkylation reaction, not only does one have the problems
of multiple alkylation and rearrangement of the cation, but the presence of strong electron
donating groups prevents reaction. Provide an explanation for this.

2. Metallocenes, like ferrocene cannot be nitrated. Why?

3. Draw the structure of the diacetylferrocene you would obtain if ferrocene were diacetylated.

4. Draw an arrow pushing mechanism for the formation of the acylium ion when acetic
anhydride reacts with phosphoric acid.

5. Provide the major organic product(s) for the following reactions.

© BrainMass Inc. brainmass.com October 25, 2018, 12:59 am ad1c9bdddf
https://brainmass.com/chemistry/organic-reactions/friedel-crafts-alkylation-and-acylation-nitration-248602

Attachments

Solution Summary

Friedel-Crafts alkylation and acylation and nitration of ferrocene and acetylferrocene are discussed in detail.

$2.19
See Also This Related BrainMass Solution

Feasible Synthetic Routes for Compounds

This problem asks to use equations to outline feasible synthetic routes to the compounds below starting with benzene or toluene and any other necessary aliphatic or inorganic reagents. Assume o- and p- isomers can be separated.

a. p-aminobenzoic acid

b. m-chloroethylbenzene

c. 2-bromo-5-(1-propenyl)aniline

See attached file for full problem description.

View Full Posting Details