Explore BrainMass

Steps in the synthesis of compounds

The professor wants us to do the following: Outline all steps in the possible synthesis of each of the following compounds from benzene and / or toluene, using any necessary aliphatic or inorganic reagents. Assume a pure para isomer that can be separated from an ortho/para mixture

a) ethylbenzene
b) phenyacetylene
c) isopropylbenzene
d) 2-phenylpropene
e) p-tertbutyltoluene
f) p-bromobenzylbromide
g) p-bromobenzoic acid
h) 1,2-diphenylethane
i) 1-phenylpropene (two ways)

© BrainMass Inc. brainmass.com August 16, 2018, 3:53 am ad1c9bdddf

Solution Preview

For these questions, one must start with the basics of aromatic substitution reactions. For a) b) and c) starting with the appropriate reagents, a simple Friedel Crafts Alkylations should work just fine.

c) This can also be done by adding benzene and propene together in strong non-coordinating acids (H2SO4 or H3PO4).

d) The can be done by adding acetone to a grignard preparation of a benzene ring. (I am sure you can figure how to do this on your own), which will first result in ...

Solution Summary

This solution is provided in 339 words. It discusses Friedel Crafts Alkylations and what kinds of chemicals would react to give the final compound.