Purchase Solution

Enantiomers and Order of Elution

Not what you're looking for?

Ask Custom Question

The enantiomers (R and S forms) of the following chiral alcohols need to be separated by a suitable CHIRAL SEPARATION method. What is a reasonable approach that will yield the separations of the two isomeric alcohols and their enantiomers. Rationalizing the approach used on the basis of chiral recognition mechanism. What will be the order of elution?

1. 1-phenyl-1-propanol
2. 2-phenyl-1-propanol

Purchase this Solution

Solution Summary

This solution describes in 303 words how to find the order of enantiomers through transformation and the four steps of the chiral recognition mechanism.

Solution Preview

Since enantiomers are physically identical, the strategy here is to convert the enantiomers, even momentarily, into diasteromers which can then be resolved either by chromatography or crystallization. Since the question asks about order of elution, I would assume the focus here would be on chiral columns and how they form diasteromers with the two enantiomers. An enantiomerically pure compound is covalently attached to a solid support. The racemic mixture is ...

Purchase this Solution

Free BrainMass Quizzes
Match Elements with their Symbols

Elements are provided: choose the matching one- or two-letter symbol for each element.


The quiz helps in revising basic concepts about thermochemistry.

Organic Chemistry Naming: Alkanes

This is a quiz which is designed to assist students with learning the nomenclature used to identify organic compounds. This quiz focuses on the organic compounds called Alkanes.

Functional groups in Organic Chemistry

You will be tested on the names of functional groups in Organic Chemistry. It is very important to know the functional groups to understand Organic reactions.