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Ethyl Acetate as an Elution Solvent

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Caffeine is soluble in ethyl acetate. Do you think that the purity of your product could be checked by TLC using ethyl acetate as an elution solvent? Explain.

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Answer: YES

Thin-Layer Chromatography (TLC) is a simple and inexpensive technique that is often used to judge the purity of a synthesized compound or to indicate the extent of progress of a chemical reaction. The TLC plate constitutes the stationary phase. The sheet is then placed in a chamber containing a small amount of solvent, ...

Solution Summary

This solutions is provided in 241 words. It discusses the possibility of using thin-layer cromatography for testing the purity of synthesized compounds as well as how this technique works to separate compounds.

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TLC and Ethyl Acetate

a) Caffeine is soluble in ethyl acetate. Do you think that the purity of the product could be checked by TLC using ethyl acetate as an elution solvent?
b) We draw color spots on TLC plates for easier visualization after elution with solvent, the plates can be "developed" in a sealed chamber containing solid iodine. Explain how the solid-vapor equilibrium operates in this instance.

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