Oseltamivir and Neuraminidase: Interaction and Bonding
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Draw a diagram of oseltamivir and label showing which atoms or functional groups could be involved in the binding of oseltamivir to the neuraminidase active site by hydrogen bonding and ionic interactions.
Identify what complementary functional group would need to be present in the neuraminidase active site for (a) hydrogen bonding and (b) ionic interactions to oseltamivir to be observed?
I only need one example of a functional group in the enzyme for each type of interaction.
Thank you!
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