Lidocaine Problem
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Lidocaine is thought to bind to receptors in its methylated form above.
Identify in writing the atoms or groups in the above compound that could be involved in its binding to a receptor via...
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Solution Summary
This solution is provided in 614 words in an attached .doc file. It describes the action of lidocaine and how it works, using diagrams to enhance understanding.
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Attached is all the information to accompany the question about how lidocaine might work through binding to receptors. All the stuff you need should be in there.
So, now the question is moving on to the mode of action of lidocaine and the way it actually makes you go numb. Lidocaine interferes with the ability of certain nerves to conduct electrical signals, which blocks the transmission of nerve impulses that carry pain messages. I'm pretty sure it does this by blocking the flow of sodium ions. In this problem, we look at some of the structural features of the molecule that may enable it to bind to the specific receptors and in doing so, block signals which would otherwise cause you to feel pain.
As the question states, lidocaine is thought to bind in its methylated form, and we have to show the parts of the molecule that could be involved in binding to the receptor via ionic bonding and hydrogen bonding. We'll ...
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