Lidocaine is thought to bond to receptors in its methylated form. Identify in writing the atoms or groups that could be involved in its bonding to a receptor via hydrogen bonding (only one example) and ionic reaction, found in the second diagram attached.
Give examples of the types of functional groups that need to be present in the receptor sites in order for these forms of bonding to take place (one example from each bonding)
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Hydrolysing lidocaine should break the amide group into an amine and a carboxylic acid. Without the diagram, I'm not sure about the 'methylated' form of lidocaine, but I can give you the rules to check the sorts of bonding possible: Hydrogen bonding: any ...
The solution draws structural formulae for lidocaine's complete hydrolysis, isolating the functional groups in the first diagram, and noting the properties of lidocaine and its bonding to receptors in certain form. Ionic reactions are also looked at, and altogether, an illustration of the properties of these functional groups and ionic bonding establishes how lidocaine bonds to receptors.
Hydrogen and Ionic Bonding
Lidocaine (see attachment for diagram) is thought to bind to receptors in its methylated form above.
Identify in writing the atoms or groups in the above compound that could be involved in its binding to a receptor via hydrogen bonding and ionic bonding.
Give examples of the types of functional group that need to be present in the receptor sites in order for these forms of binding to take place (one example for each form of binding).View Full Posting Details