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Autoimmune Disease

Lab mice are immunized with a measles vaccine. When the mice are challenged with the measles virus to test the strength of their immunity, the memory cells do not completely prevent replication of the measles virus. The virus undergoes a few rounds of replication before the immune response is observed. You have developed a strain of mice with a much faster response to a viral challenge, but these mice often develop an autoimmune disease. Discuss the connection between the speed of response and an autoimmune disease.

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The immune system of mammals, in particular mice, have a few mechanisms for ensuring that the whatever is being attacked is supposed to be attacked. The reason why a normal strain of mice will at first experience a few rounds of replication of a virus is because a systemic response to the infection doesn't occur until a large number of antigens are detected. This provides a better sample for the immune system to accurately identify the infectious agent. Various immune cells will basically collect data about the invading pathogen. Multiple ...

Solution Summary

The expert examines autoimmune disease immunizations. The connection between the speed of response and an autoimmune disease is given.