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conversion of proto-oncogenes to oncogenes

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What mechanisms are involved in conversion of proto-oncogenes to oncogenes? Give examples.

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Solution Summary

This solution explains, with examples, how proto-oncogenes can convert into oncogenes that promote tumor development.

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Proto-oncogenes are involved in the control of cell proliferation, a tightly regulated process in normal cells. Normally there is very tight regulation of this process, to avoid inappropriate cell division, which could lead to the development of tumors. However when these proto-oncogenes convert to oncogenes, this regulation breaks down, leading to an ...

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