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    Sickle Cell Disease (SCD)

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    You have been asked to create a teaching scenario for a group of students in your discipline. Choose either a disease process discussed in this course, or be creative and choose a disease process you are interested in. Create a Word document or PowerPoint presentation of a fabricated case study that must include:

    1. Complete symptoms & history of a fabricated patient with your chosen disease
    2. Physical findings of your fabricated patient that are consistent with your chosen disease
    3. Diagnostic methods (lab and x-ray) used for the patient. Explain what the common exams would be used for your chosen disease. Include images, results etc.
    4. Other possible diagnoses that could be ruled out. Explain why these could be ruled out.
    5. At least 2 treatment options for this disease.
    6. Short and long term prognosis.
    7. How this disease relates to the age of patient as far as onset, symptoms, etc.
    8. Use at least 3 scholarly journals as sources. Include them in APA format at the end of your case study.
    Here are some examples of case studies:
    University of Minnesota Case Studies
    Upstate Medical University
    Indiana University School of Medicine Clinical Cases

    And a sample of what you can do for your assignment:
    Sample PowerPoint Case Study.

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    Solution Preview

    I have explained in details sickle cell disease and also used an imaginary fabricated case. Attached are the PowerPoint Slides which explains in details the above. The PowerPoint slides have 2 parts:
    1. Part 1 describes the Sickle Cell Disease in details.
    2. Part 2 Imagines a Case study of an imaginary patient named "Mike" and explains in details his symptoms, diagnosis, treatment.

    There is lot of information in these slides and appropriate references. Please go through the slides, try to understand the concept and you'll be able to take out the relevant portions.
    ** I have also provided the text below.

    General Information of Sickle cell Disease (SCD):
    SCD is a serious disorder in which the body makes sickle-shaped red blood cells making the cells look like a crescent.
    SCD is a hereditary disorder where patients inherit a mutated copy of β-globin gene (βs) from their parents. This results in the formation of a defective Hemoglobin molecule. These defective hemoglobin form polymers under low oxygen (hypoxic) environment which makes the red blood cells (RBC) to have a "Sickle" or "Crescent" shape.
    Sickled shaped RBC tend to be sticky and rigid and hence they block the blood vessels resulting in vaso-occlution leading to less oxygen being supplied to organs causing stroke, infarction, tissue fibrosis and necrosis.

    SCD Symptoms:
    Respiratory: Shortness of breath
    CNS: Dizziness, fatigue, fainting, headaches
    Skin: Paleness, Coldness, Yellowing
    Eyes: Yellowing
    Muscle: Weakness
    Blood Pressure: low blood pressure
    Heart: Palpitation, rapid heart rate, Chest pain, Angina, ...

    Solution Summary

    The solution explains Sickle Cell Disease, its symptoms, diagnosis, treatment and epidemiology. It also talks about a case study of an imaginary SCD patient and explains the mode of diagnosis and treatment by using a bone marrow transplantation.